zvigadzirwa
Yakakwira Hunhu L-Glutathione Yakaderedzwa CAS 70-18-8 yeSkin Care Glutathione
Product details
MF: C10H17N3O6S
MW: 307.32
CAS: 70-18-8
1.Glutathione inonzi tripeptide condensed ne glutamic acid, cysteine uye glycine kuburikidza ne peptide bonds.Ndiyo inonyanya kukosha yakaderera molecular mercaptan mumammalian masero pasi pe antioxidant kusagadzikana.
2.Glutathione (GSH) inhengo ye tripeptide inoumbwa ne condensation ye glutamic acid, cysteine uye glycine kuburikidza ne peptide bonds.Iro zita remakemikari ndiro γ- Iyo yemaitiro fomula yel-glutamyl-l-cysteyl-glycine inoratidzwa mumufananidzo 1chemicalbook.Zvinoenderana nechimiro chechimiro muchimiro, GSH yakasiyana nemamwe mapeptide nemapuroteni.Kune yakakosha peptide bond mumorekuru wayo, iyo inogadzirwa ne glutamic acid γ- Carboxyl (- COOH) uye cysteine α- Peptide bond inoumbwa ne condensation yeamino - (- NH2).
3.The molecular weight of glutathione is 307.33, the melting point is 189 ~ 193 ℃ (decomposition), crystal haina ruvara, yakajeka, slender column, uye isoelectric point ndeye 5.93.Inonyungudika mumvura, dilute doro, liquid ammonia uye methyl formamide, asi isinganyunguriki mudoro, ether uye acetone.GSH chete ine physiological chiitiko muzvisikwa, uye GSSG inogona kutamba yakakosha basa remuviri mushure mekuderedzwa.GSH haisi nyore kuchengeta pasi pekuita kwemvura yakakwirira, uye inogona kuchengetwa zvakasimba kwenguva yakareba chete kana basa remvura richidzorwa pasi pe0.3.Zvidzidzo zvakaratidza kuti muvhitamini ccchemicalbook aqueous solution ine GSH (ph3.3), nekuda kwekuderera kwakasimba kwevhitamini C, GSH mumushonga haizove oxidized kuGSSG, asi kukurumidza kupera kwayo kunowedzera;GSSG muvhitamini C aqueous solution haizoshandurwe kuita GSH, uye kugadzikana kwayo kwekuchengetedza kwakanaka kwazvo.Uyezve, GSSG inobatwa nemuromo inogona kuderedzwa kusvika kuGSH muchikamu chepamusoro chemukati mudumbu, uye pamusoro pemasero maduku epithelial epithelial γ- GTP (iyo inoparadza GSH mu glutamic acid uye Cys Gly) uye dipeptidase inogonawo kutamba zvakakosha zvemuviri. mabasa.
4.Glutathione inowanikwa zvakanyanya mumhuka nemiti, uye zvinyorwa zvayo mumbiriso yemubiki, gorosi yegorosi uye chiropa chemhuka yakakwirira kwazvo, kusvika ku100 ~ 1000mg / 100g;Yakapfumawo muropa revanhu neremhuka, se26chemicalbook ~ 34mg/100g muropa revanhu, 58 ~ 73mg/100g muropa rehuku, 10 ~ 15mg/100g muropa renguruve uye 14 ~ 22mg/100g muropa rembwa.GSH inowanikwawo mumiriwo yakawanda, mbatatisi uye zviyo.
Application
1. Yakaderedzwa glutathione idiki molecule peptide, iyo inowanikwa muhuwandu hwakawanda muzvisikwa, kunyanya mumasero echiropa.Inogona kuchengetedza chiropa cell membrane, kukurudzira chiropa enzyme basa, uye kusanganisa nemakemikari akawanda ane chepfu mumakemikaribook kuti abvise.Iyo ine mhedzisiro yakanaka pakukuvadzwa kwechiropa, chiropa cirrhosis uye zvimwe zvirwere zvinokonzerwa nehupfu hwezvinodhaka, kudhakwa uye zvimwe zvikonzero.
2.Iyo ine mabasa e-antioxidation, scavenging free radicals, detoxification, kusimbisa hutachiona, kunonoka kukwegura, anti-cancer, anti-radicals kukuvara uye zvichingodaro.
3.Biochemical reagents uye antidotes inonyanya kushandiswa kune chepfu yesimbi inorema, acrylonitrile, fluoride, carbon monoxide uye organic solvents.
4.Endogenous antioxidants inoita basa rinokosha mukuderedza reactive oxygen marudzi akaumbwa panguva ye cell metabolism uye kamwe-kamwe kufema.Glutathione-S-transferase inokonzeresa kuumbwa kweglutathione sulfide ine xenobiotics, leukotrienes uye mamwe mamorekuru ane electrophilic centers.Glutathione inoumbawo disulfide zvisungo nema cysteine masara mumapuroteni.Kuburikidza nemaitiro aya, inogona kuva nechishamiso chekudzikisa kushanda kweaanticancer agents.
